KIT Antikörper (truncated)

Produktnummer ABIN2464038

Der Maus Monoklonal anti-KIT Antikörper (Klon 8D7B4-8D7D4-7H6B2-7H6B12) (ABIN2464038) detektiert spezifisch KIT in ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für KIT Antikörper (truncated) (ABIN2464038)

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 8D7B4-8D7D4-7H6B2-7H6B12

Produktdetails anti-KIT Antikörper

Bindungsspezifität: truncated

Aufreinigung: Antibody is purified by protein A affinity chromatography.

Immunogen: Ni-NTA purified truncated recombinant C-kit expressed in E. Coli strain BL21 (DE3).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Dilution
ELISA:Propose dilution 1:10,000
Determining optimal working dilutions by titration test.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Handhabung: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Lagerung: -20 °C

Informationen zur Lagerung: C-Kit monoclonal antibody can be stored at -20 °C, stable for one year.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: CKit

Hintergrund: C-kit (CD117,145 kDa) functions as a tyrosine kinase receptor which becomes activated upon binding of its ligand SCF (stem-cell factor), the C-kit gene encodes the human homolog of the proto-oncogene c-kit. which was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.

Gen-ID: 3815

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity