KHDRBS1 Antikörper

Produktnummer ABIN2462221

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch KHDRBS1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für KHDRBS1 Antikörper (ABIN2462221)

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KHDRBS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KHDRBS1 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human KHDRBS1.

Anwendungsinformationen

Applikationshinweise: KHDRBS1 antibody can be used for detection of KHDRBS1 by ELISA at 1:12500. KHDRBS1 antibody can be used for detection of KHDRBS1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store KHDRBS1 antibody at -20 °C.

Details zu KHDRBS1

Target: KHDRBS1 (KH Domain Containing, RNA Binding, Signal Transduction Associated 1 (KHDRBS1))

Andere Bezeichnung: KHDRBS1

Hintergrund: KHDRBS1 recruited and tyrosine phosphorylated by several receptor systems, for example the T-cell, leptin and insulin receptors. Once phosphorylated, KHDRBS1 functions as an adapter protein in signal transduction cascades by binding to SH2 and SH3 domain-containing proteins. KHDRBS1 play a role in G2-M progression in the cell cycle. It represses CBP-dependent transcriptional activation apparently by competing with other nuclear factors for binding to CBP. KHDRBS1 also acts as a putative regulator of mRNA stability and/or translation rates and mediates mRNA nuclear export.

Molekulargewicht: 48 kDa

Gen-ID: 10657

NCBI Accession: NP_006550

UniProt: Q07666

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Autophagie