TAB2 Antikörper

Produktnummer ABIN2460457

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TAB2 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte und Hund.

Kurzübersicht für TAB2 Antikörper (ABIN2460457)

Target: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Reaktivität: Human, Maus, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-TAB2 Antikörper

Aufreinigung: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K7IP2.

Anwendungsinformationen

Applikationshinweise: MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by ELISA at 1:312500. MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by western blot at 2.0/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Konzentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handhabung: As with any antibody avoid repeat freeze-thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAP3K7IP2 antibody at -20 °C.

Details zu TAB2

Target: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Andere Bezeichnung: MAP3K7IP2

Hintergrund: MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Molekulargewicht: 76 kDa

Gen-ID: 23118

NCBI Accession: NP_055908

UniProt: Q9NYJ8

Pathways: T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway