PKM2 Antikörper (Asn491, C-Term) (HRP)

Produktnummer ABIN2336512

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PKM2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PKM2 Antikörper (Asn491, C-Term) (HRP) (ABIN2336512)

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PKM2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PKM2 Antikörper (HRP)

Bindungsspezifität: Asn491, C-Term

Spezifität: Recognizes human PKM2.

Kreuzreaktivität: Human, Maus

Kreuzreaktivität (Details): Calculated cross reactivity: Hu Mo

Produktmerkmale: PKM2, CT (N491) (Pyruvate Kinase, Isozymes M1/M2, Pyruvate Kinase Muscle Isozyme, Cytosolic Thyroid Hormone-binding Protein, CTHBP, Opa-interacting Protein 3, OIP-3, Pyruvate Kinase 2/3, Thyroid Hormone-binding Protein 1, THBP1, Tumor M2-PK, p58, PKM, OIP3, PK2, PK3) (Azide free) (HRP)

Aufreinigung: Purified by Protein G affinity chromatography.

Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 476-505 in the C-terminal region of human PKM2, UniProt Accession #NP_002645.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).

Konservierungsmittel: Without preservative

Lagerung: -20 °C

Informationen zur Lagerung: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer.

Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Details zu PKM2

Target: PKM2 (Pyruvate Kinase M2 (PKM2))

Andere Bezeichnung: PKM2

Hintergrund: PKM2 is a pyruvate kinase that catalyzes the production of phosphoenolpyruvate from pyruvate and ATP. This protein has been shown to interact with thyroid hormone, and thus may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis.

NCBI Accession: NP_002645

UniProt: P14618

Pathways: Warburg Effekt