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IL1R2 Antikörper

IL1R2 Reaktivität: Human IA Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN2192180
$605.98
Zzgl. Versandkosten $45.00
100 μg
Lieferung in 6 bis 8 Werktagen
  • Target Alle IL1R2 Antikörper anzeigen
    IL1R2
    Reaktivität
    • 89
    • 25
    • 18
    Human
    Wirt
    • 60
    • 24
    • 7
    • 1
    Kaninchen
    Klonalität
    • 69
    • 22
    Polyklonal
    Konjugat
    • 47
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IL1R2 Antikörper ist unkonjugiert
    Applikation
    • 58
    • 50
    • 27
    • 13
    • 13
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunoassay (IA)
    Sterilität
    0.2 μm filtered
  • Applikationshinweise
    For immuno assays dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Haltbarkeit
    12 months
  • Mantovani, Muzio, Ghezzi, Colotta, Introna: "Regulation of inhibitory pathways of the interleukin-1 system." in: Annals of the New York Academy of Sciences, Vol. 840, pp. 338-51, (1998) (PubMed).

  • Target
    IL1R2
    Abstract
    IL1R2 Produkte
    Synonyme
    CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB, Il1r-2, IL-1R2, interleukin 1 receptor type 2, interleukin 1 receptor, type II, interleukin-like, IL1R2, Il1r2, KK34
    Hintergrund
    The antibody reacts specificly with human Interleukin (IL-1) R II. The IL-1 system includes two agonists (IL- 1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 R I and IL-1 R II) and the IL-1 receptor accessory protein. The IL-1 R II is part of the antagonistic IL-1 mechanism. It is also known as decoy receptor and is a non signalling molecule which functions by capturing IL-1 and preventing it from interacting with the signalling IL-1 R I. The decoy IL-1 R II can after binding to IL-1 also recruit the IL-1 receptor accessory protein and thus inhibit by coreceptor competition. Further a soluble form of IL-1 R II exists which is shed, a process in which matrix metalloproteases have been found to play a role, by various cells including monocytes, polymorphonuclear cells, B cells and fibroblasts.
    Pathways
    NF-kappaB Signalweg
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