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Complement Factor B Antikörper (N-Term)

CFB Reaktivität: Human WB, IHC, ELISA, FACS, IHC (fro) Wirt: Maus Monoclonal unconjugated
Produktnummer ABIN206664
  • Target Alle Complement Factor B (CFB) Antikörper anzeigen
    Complement Factor B (CFB)
    Bindungsspezifität
    • 15
    • 10
    • 9
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 76
    • 44
    • 34
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 92
    • 17
    • 3
    Maus
    Klonalität
    • 94
    • 17
    • 1
    Monoklonal
    Konjugat
    • 48
    • 18
    • 16
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Complement Factor B Antikörper ist unkonjugiert
    Applikation
    • 83
    • 43
    • 30
    • 16
    • 13
    • 13
    • 12
    • 10
    • 9
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Spezifität
    Recognizes the Bb fragment of 90 kD human complement factor B, present in blood serum. C3b associates with complement factor B, inducing conformational change which enables complement factor D to cleave the N-terminal of complement factor B, the Ba subunit, leaving the 63 kD Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation. Binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
    Aufreinigung
    Protein A purified
    Immunogen
    Human factor B.
    Isotyp
    IgG1
    Top Product
    Discover our top product CFB Primärantikörper
  • Applikationshinweise
    Approved: ELISA, Flo, IHC, IHC-Fr, WB

    Usage: ELISA: LS-C44981 binds to both the Bb fragment and complement factor B so is not suitable for all ELISA applications.
    Kommentare

    Target Species of Antibody: Human

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Borate buffered saline,  pH 8.4, 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    Complement Factor B (CFB)
    Andere Bezeichnung
    CFB / Complement Factor B (CFB Produkte)
    Hintergrund
    Name/Gene ID: CFB
    Subfamily: Serine S1
    Family: Protease

    Synonyms: CFB, AHUS4, B-factor, properdin, C3/C5 convertase, CFAB, C3 proaccelerator, C3 proactivator, Complement factor B, Complement protein Factor B, Glycine-rich beta-glycoprotein, GBG, Factor B, FB, Glycine-rich beta glycoprotein, PBF2, BF, BFD, FBI12, H2-Bf, Properdin factor B
    Gen-ID
    629
    UniProt
    P00751
    Pathways
    Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process
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