ZAP70 Antikörper (AA 280-309) (FITC)
Kurzübersicht für ZAP70 Antikörper (AA 280-309) (FITC) (ABIN206033)
Target
Alle ZAP70 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 280-309
-
Spezifität
- Recognizes human ZAP-70, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
-
Aufreinigung
- Purified
-
Immunogen
- Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.
-
Isotyp
- IgG1
-
-
-
-
Applikationshinweise
-
Approved: Flo
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. -
Kommentare
-
Target Species of Antibody: Human
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- PBS, 0.09 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
-
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
-
Andere Bezeichnung
- ZAP70
-
Hintergrund
-
Name/Gene ID: ZAP70
Subfamily: Syk/ZAP70
Family: Protein Kinase
Synonyms: ZAP70, 70 kDa zeta-associated protein, SRK, STCD, STD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, TZK, ZAP-70, Zeta-associated protein 70 -
Gen-ID
- 7535
-
UniProt
- P43403
-
Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
Target
-