ZAP70 Antikörper (AA 280-309) (FITC)
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- Target Alle ZAP70 Antikörper anzeigen
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
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Bindungsspezifität
- AA 280-309
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser ZAP70 Antikörper ist konjugiert mit FITC
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- Recognizes human ZAP-70, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.
- Aufreinigung
- Purified
- Immunogen
- Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.
- Isotyp
- IgG1
- Top Product
- Discover our top product ZAP70 Primärantikörper
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- Applikationshinweise
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Approved: Flo
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Kommentare
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Target Species of Antibody: Human
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- PBS, 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- Target
- ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
- Andere Bezeichnung
- ZAP70 (ZAP70 Produkte)
- Hintergrund
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Name/Gene ID: ZAP70
Subfamily: Syk/ZAP70
Family: Protein Kinase
Synonyms: ZAP70, 70 kDa zeta-associated protein, SRK, STCD, STD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, TZK, ZAP-70, Zeta-associated protein 70 - Gen-ID
- 7535
- UniProt
- P43403
- Pathways
- T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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