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ZAP70 Antikörper (AA 280-309) (FITC)

Der Maus Monoklonal Anti-ZAP70 Antikörper wurde für FACS validiert. Er ist geeignet, ZAP70 in Proben von Human zu detektieren.
Produktnummer ABIN206033

Kurzübersicht für ZAP70 Antikörper (AA 280-309) (FITC) (ABIN206033)

Target

Alle ZAP70 Antikörper anzeigen
ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

Reaktivität

  • 299
  • 136
  • 46
  • 8
  • 7
  • 6
  • 6
  • 6
  • 5
  • 3
  • 3
  • 2
  • 1
Human

Wirt

  • 211
  • 90
  • 2
  • 2
  • 1
Maus

Klonalität

  • 184
  • 121
Monoklonal

Konjugat

  • 139
  • 18
  • 14
  • 11
  • 9
  • 6
  • 6
  • 5
  • 5
  • 5
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  • 4
  • 4
  • 4
  • 4
  • 4
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  • 4
  • 4
  • 4
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  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser ZAP70 Antikörper ist konjugiert mit FITC

Applikation

  • 202
  • 135
  • 92
  • 88
  • 65
  • 52
  • 52
  • 34
  • 33
  • 22
  • 20
  • 14
  • 12
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • Bindungsspezifität

    • 42
    • 34
    • 28
    • 27
    • 21
    • 20
    • 16
    • 10
    • 10
    • 9
    • 8
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    AA 280-309

    Spezifität

    Recognizes human ZAP-70, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukaemia.

    Aufreinigung

    Purified

    Immunogen

    Peptide corresponding to amino acid residues 280-309 of human ZAP-70, conjugated to KLH.

    Isotyp

    IgG1
  • Applikationshinweise

    Approved: Flo

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

    Kommentare

    Target Species of Antibody: Human

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Target

    ZAP70 (zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))

    Andere Bezeichnung

    ZAP70

    Hintergrund

    Name/Gene ID: ZAP70
    Subfamily: Syk/ZAP70
    Family: Protein Kinase

    Synonyms: ZAP70, 70 kDa zeta-associated protein, SRK, STCD, STD, Syk-related tyrosine kinase, Tyrosine-protein kinase ZAP-70, TZK, ZAP-70, Zeta-associated protein 70

    Gen-ID

    7535

    UniProt

    P43403

    Pathways

    T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway
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