Connexin 43/GJA1 Antikörper (C-Term)

Produktnummer ABIN199020

Dieses Anti-Connexin 43/GJA1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Connexin 43/GJA1 in WB, ELISA, IF und IHC (p). Geeignet für Human, Ratte, Maus und Hund.

Kurzübersicht für Connexin 43/GJA1 Antikörper (C-Term) (ABIN199020)

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reaktivität: Human, Ratte, Maus, Hund

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Connexin 43/GJA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Connexin 43/GJA1 Antikörper

Bindungsspezifität: C-Term

Spezifität: Recognizes rat Connexin 43 only when the serine at residue 368 is unphosphorylated. Does recognize Connexin 43 if it is phosphorylated at sites other than Ser368. In some cell types, cross-reactivity with a ~70kD protein of unknown identity has been observed. This cross-reactivity is likely due to a shared epitope. Species cross-reactivity: Canine, human, mouse.

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to a cytoplasmic sequence located near the C-terminus of rat Connexin 43.

Type of Immunogen: Synthetic peptide

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunolocalization and Electron Microscopy. ELISA: 0.1-1 ug/ml. Western Blot: 1-3 ug/ml.

Kommentare:

Target Species of Antibody: Rat

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu Connexin 43/GJA1

Target: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Andere Bezeichnung: GJA1 / CX43 / Connexin 43

Hintergrund: Name/Gene ID: GJA1
Subfamily: Connexin
Family: Ion Channel

Synonyms: GJA1, Connexin-43, DFNB38, Connexin 43, Gap junction alpha-1 protein, GJAL, HSS, Gap junction protein alpha 1, ODDD, ODD, AVSD3, CX43, HLHS1, ODOD, SDTY3

Gen-ID: 2697

UniProt: P17302

Pathways: MAPK Signalweg, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization