PDGFRB Antikörper (Extracellular Domain)

Produktnummer ABIN198270

Der Maus Monoklonal anti-PDGFRB Antikörper (Klon PR7212) (ABIN198270) detektiert spezifisch PDGFRB in WB, IHC, IHC (p), FACS, IP und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Affe und Pavian.

Kurzübersicht für PDGFRB Antikörper (Extracellular Domain) (ABIN198270)

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Reaktivität: Human, Affe, Pavian

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDGFRB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: PR7212

Produktdetails anti-PDGFRB Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Recognizes the extracellular domain of the human PDGF receptor beta subunit. This was confirmed in binding studies using several different cell lines and by its ability to immunoprecipitate PDGF receptor beta complexed with 125I-PDGF-BB. Does not recognize PDGF receptor alpha. PDGF receptor beta is a member of the class III receptor tyrosine kinase family that also includes M-CSF receptor, SCF receptor and Flt-3. Binding of PDGF-BB induces receptor homodimerization or heterodimerization with PDGF receptor alpha.

Keine Kreuzreaktivität: Maus, Ratte (Rattus)

Aufreinigung: Protein G purified

Immunogen: Human skin fibroblast cell membrane extracts.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (25 μg/mL), IHC, IHC-Fr, IHC-P (25 μg/mL), IP, WB

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: 4°C or -20°C, Avoid freeze-thaw cycles.

Details zu PDGFRB

Target: PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))

Andere Bezeichnung: PDGFRB / PDGFR beta

Hintergrund: Name/Gene ID: PDGFRB
Subfamily: PDGF Receptor
Family: Protein Kinase

Synonyms: PDGFRB, CD140B, Beta pdfgr, Beta type PDGFR, BPDGFR, CD140b antigen, IBGC4, JTK12, PDGF-beta R, PDGF-R-beta, PDGFR, PDGFRbeta, PDGF receptor beta, PDGF-R, PDGFbetaR, PDGFR Beta, PDGFR-1, PDGFR-beta, BetaPDGFR, Pdgf beta-receptor, PDGFR1, PDGFRB/CEV14 fusion gene

Gen-ID: 5159

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling