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CDK2 Antikörper (Thr160)
CDK2
Reaktivität: Human, Maus, Ratte
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-CDK2 Antikörper
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Target
Alle CDK2 Antikörper anzeigen
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Bindungsspezifität
Alle Epitope für CDK2 Antikörper
Thr160
Reaktivität
Alle Reaktivitäten für CDK2 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für CDK2 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CDK2 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CDK2 Antikörper
Dieser CDK2 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CDK2 Antikörper
Western Blotting (WB)
Sequenz
T-Y-TP-H-E
Spezifität
This antibody detects endogenous levels of total CDK2 protein.
Aufreinigung
Affinity-chromatography using epitope-specific immunogen
Immunogen
Synthesized non-phosphopeptide derived from human CDK2 around the phosphorylation site of threonine160.
Top Product
Discover our top product CDK2 Primärantikörper
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Anwendungsinformationen
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Applikationshinweise
Western blot (1: 500 - 1: 1000). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
-20 °C
Informationen zur Lagerung
Store (in aliquots) at -20 °C.
Details zu CDK2
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Target
CDK2
(Cyclin-Dependent Kinase 2 (CDK2))
Andere Bezeichnung
CDK2 (CDK2 Produkte )
Synonyme
p33(CDK2) antikoerper, A630093N05Rik antikoerper, wu:fa10c02 antikoerper, zgc:56598 antikoerper, zgc:77684 antikoerper, eg1 antikoerper, CDKN2 antikoerper, cdk2L antikoerper, cyclin dependent kinase 2 antikoerper, cyclin-dependent kinase 2 antikoerper, cyclin-dependent kinase 2 S homeolog antikoerper, CDK2 antikoerper, Cdk2 antikoerper, cdk2 antikoerper, cdk2.S antikoerper
Hintergrund
Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase
Gen-ID
1017
NCBI Accession
NP_001789
UniProt
P24941
Pathways
PI3K-Akt Signalweg , Zellzyklus , Mitotic G1-G1/S Phases , DNA Replication , M Phase , Synthesis of DNA
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