TPP1 Antikörper (AA 66-294)

Produktnummer ABIN1886604

Der Kaninchen Polyklonal anti-TPP1 Antikörper (ABIN1886604) detektiert spezifisch TPP1 in WB, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für TPP1 Antikörper (AA 66-294) (ABIN1886604)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TPP1 Antikörper

Bindungsspezifität: AA 66-294

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 66 and 294 of human TPP1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: CLN2

Hintergrund: This gene encodes a member of the sedolisin family of serine proteases.The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity.It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification.Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.[provided by RefSeq]

Molekulargewicht: 61 kDa

Gen-ID: 1200

Pathways: Zellzyklus, ER-Nucleus Signaling