DMBT1 Antikörper (AA 2025-2273)

Produktnummer ABIN1886177

Der Kaninchen Polyklonal Anti-DMBT1-Antikörper wurde für WB validiert. Er ist geeignet, DMBT1 in Proben von Human zu detektieren.

Kurzübersicht für DMBT1 Antikörper (AA 2025-2273) (ABIN1886177)

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DMBT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DMBT1 Antikörper

Bindungsspezifität: AA 2025-2273

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 2025 and 2273 of Human DMBT1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu DMBT1

Target: DMBT1 (Deleted in Malignant Brain Tumors 1 (DMBT1))

Andere Bezeichnung: gp340

Hintergrund: Loss of sequences from human chromosome 10q has been associated with the progression of human cancers.The gene DMBT1 was originally isolated based on its deletion in a medulloblastoma cell line.DMBT1 is expressed with transcripts of 6.0, 7.5, and 8.0 kb in fetal lung and with one transcript of 8.0 kb in adult lung, although the 7.5 kb transcript has not been characterized.The DMBT1 protein is a glycoprotein containing multiple scavenger receptor cysteine-rich (SRCR) domains separated by SRCR-interspersed domains (SID).Transcript variant 2 (8.0 kb) has been shown to bind surfactant protein D independently of carbohydrate recognition.This indicates that DMBT1 may not be a classical tumor supressor gene, but rather play a role in the interaction of tumor cells and the immune system.[provided by RefSeq]

Molekulargewicht: 260 kDa

Gen-ID: 1755

NCBI Accession: NM_017579, NP_060049

Pathways: Activation of Innate immune Response