FGFRL1 Antikörper (AA 150-486)

Produktnummer ABIN1886062

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FGFRL1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FGFRL1 Antikörper (AA 150-486) (ABIN1886062)

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGFRL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FGFRL1 Antikörper

Bindungsspezifität: AA 150-486

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 150 and 486 of Human FGFRL1

Anwendungsinformationen

Applikationshinweise: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: Biohazard Informations: This product contains thimerosal which is hazardous.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Details zu FGFRL1

Target: FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))

Andere Bezeichnung: FGFR-5

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution.FGFR family members differ from one another in their ligand affinities and tissue distribution.A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain.The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation.A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain.The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling.Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.[provided by RefSeq]

Molekulargewicht: 55 kDa

Gen-ID: 53834

NCBI Accession: NP_001004356, NM_001004356

Pathways: RTK Signalweg