Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

XPC Antikörper (N-Term)

This anti-XPC antibody (ABIN1882000) is a Rabbit Polyclonal antibody detecting XPC in WB. Suitable for Human.
Produktnummer ABIN1882000

Kurzübersicht für XPC Antikörper (N-Term) (ABIN1882000)

Target

Alle XPC Antikörper anzeigen
XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reaktivität

  • 45
  • 7
  • 5
  • 1
Human

Wirt

  • 45
  • 8
Kaninchen

Klonalität

  • 46
  • 7
Polyklonal

Konjugat

  • 35
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser XPC Antikörper ist unkonjugiert

Applikation

  • 37
  • 23
  • 16
  • 13
  • 12
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)

Klon

RB40964
  • Bindungsspezifität

    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 154-183, N-Term

    Aufreinigung

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    Immunogen

    This XPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the N-terminal region of human XPC.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Haltbarkeit

    6 months
  • Stern, Lin, Figueroa, Kelsey, Kiltie, Yuan, Matullo, Fletcher, Benhamou, Taylor, Placidi, Zhang, Steineck, Rothman, Kogevinas, Silverman, Malats, Chanock, Wu, Karagas: "Polymorphisms in DNA repair genes, smoking, and bladder cancer risk: findings from the international consortium of bladder cancer." in: Cancer research, Vol. 69, Issue 17, pp. 6857-64, (2009) (PubMed).

  • Target

    XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

    Andere Bezeichnung

    XPC

    Hintergrund

    This gene encodes a component of the nucleotide excision repair (NER) pathway. There are multiple components involved in the NER pathway, including Xeroderma pigmentosum (XP) A-G and V, Cockayne syndrome (CS) A and B, and trichothiodystrophy (TTD) group A, etc. This component, XPC, plays an important role in the early steps of global genome NER, especially in damage recognition, open complex formation, and repair protein complex formation. Mutations in this gene or some other NER components result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene.

    Molekulargewicht

    105953

    NCBI Accession

    NP_001139241, NP_004619

    UniProt

    Q01831

    Pathways

    p53 Signalweg, DNA Reparatur
Sie sind hier:
Chat with us!