ULK1 Antikörper (pSer556)
Kurzübersicht für ULK1 Antikörper (pSer556) (ABIN1881979)
Target
Alle ULK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer556
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Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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Immunogen
- This ULK1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S556 of human ULK1.
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Isotyp
- Ig Fraction
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Applikationshinweise
- IF: 1:200. DB: 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Haltbarkeit
- 6 months
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: "Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent." in: Neuro-oncology, Vol. 12, Issue 5, pp. 473-81, (2010) (PubMed).
: "Properties of human malignant glioma cells in vitro." in: Medical biology, Vol. 56, Issue 4, pp. 184-93, (1978) (PubMed).
: "Determinants for the establishment of permanent tissue culture lines from human gliomas." in: Acta pathologica et microbiologica Scandinavica. Section A, Pathology, Vol. 81, Issue 6, pp. 791-805, (1974) (PubMed).
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: "Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent." in: Neuro-oncology, Vol. 12, Issue 5, pp. 473-81, (2010) (PubMed).
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- ULK1 (Unc-51 Like Kinase 1 (ULK1))
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Andere Bezeichnung
- ULK1
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Hintergrund
- Involved in autophagy. Required for autophagosome formation (By similarity). Target of the TOR kinase signaling pathway that regulates autophagy through the control of phosphorylation status of ATG13/KIAA0652 and ULK1, and the regulation of the ATG13-ULK1-RB1CC1 complex (By similarity). Phosphorylates ATG13/KIAA0652. Involved in axon growth (By similarity). Plays an essential role in neurite extension of cerebellar granule cells (By similarity).
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Molekulargewicht
- 112631
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NCBI Accession
- NP_003556
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UniProt
- O75385
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Pathways
- Regulation of Cell Size, Autophagie
Target
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