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MAP1LC3A Antikörper (pSer12)

MAP1LC3A Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB30640 unconjugated
Produktnummer ABIN1881524
  • Target Alle MAP1LC3A Antikörper anzeigen
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Bindungsspezifität
    • 23
    • 21
    • 20
    • 15
    • 13
    • 11
    • 10
    • 10
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer12
    Reaktivität
    • 212
    • 106
    • 87
    • 12
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 174
    • 44
    • 2
    Kaninchen
    Klonalität
    • 165
    • 55
    Polyklonal
    Konjugat
    • 109
    • 18
    • 15
    • 14
    • 14
    • 13
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser MAP1LC3A Antikörper ist unkonjugiert
    Applikation
    • 199
    • 95
    • 74
    • 47
    • 33
    • 32
    • 29
    • 14
    • 14
    • 14
    • 11
    • 9
    • 9
    • 6
    • 5
    Dot Blot (DB)
    Homologie
    Zf, B, M, Rat
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This MAP1LC3A Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S12 of human MAP1LC3A.
    Klon
    RB30640
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAP1LC3A Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Scherz-Shouval, Weidberg, Gonen, Wilder, Elazar, Oren: "p53-dependent regulation of autophagy protein LC3 supports cancer cell survival under prolonged starvation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18511-6, (2010) (PubMed).

    Cherra, Kulich, Uechi, Balasubramani, Mountzouris, Day, Chu: "Regulation of the autophagy protein LC3 by phosphorylation." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 533-9, (2010) (PubMed).

    Namgoong, Khanal, Cho, Lim, Oh, Kang, Shim, Shim, Yoo, Choi: "The prolyl isomerase Pin1 induces LC-3 expression and mediates tamoxifen resistance in breast cancer." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23829-41, (2010) (PubMed).

    Jiang, Cheng, Liu, Peng, Feng: "Protein kinase C inhibits autophagy and phosphorylates LC3." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 471-6, (2010) (PubMed).

    Gao, Cao, Bao, Zuo, Xie, Cai, Fu, Zhang, Wu, Zhang, Chen: "Autophagy negatively regulates Wnt signalling by promoting Dishevelled degradation." in: Nature cell biology, Vol. 12, Issue 8, pp. 781-90, (2010) (PubMed).

  • Target
    MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))
    Andere Bezeichnung
    MAP1LC3A (MAP1LC3A Produkte)
    Synonyme
    ATG8E antikoerper, LC3 antikoerper, LC3A antikoerper, MAP1ALC3 antikoerper, MAP1BLC3 antikoerper, 1010001H21Rik antikoerper, 4922501H04Rik antikoerper, LC3a antikoerper, MGC69006 antikoerper, zgc:77094 antikoerper, MGC89867 antikoerper, MAP1LC3A antikoerper, map1lc3a antikoerper, microtubule associated protein 1 light chain 3 alpha antikoerper, microtubule-associated protein 1 light chain 3 alpha antikoerper, microtubule associated protein 1 light chain 3 alpha S homeolog antikoerper, MAP1LC3A antikoerper, Map1lc3a antikoerper, map1lc3a.S antikoerper, map1lc3a antikoerper
    Hintergrund
    MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene.
    NCBI Accession
    NP_115903, NP_852610
    UniProt
    Q9H492, Q9GZQ8
    Pathways
    Autophagie
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