CFP Antikörper

Produktnummer ABIN181117

Dieser Maus Monoklonal Antikörper erkennt spezifisch CFP in EIA, IHC (fro) und Func. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CFP Antikörper (ABIN181117)

Target: CFP (Complement Factor P (CFP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CFP Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Klon: 01-10-18

Produktdetails anti-CFP Antikörper

Spezifität: This antibody recognises human factor P, a 53 kDa glycosylated protein present in blood serum.

Produktmerkmale: Synonyms: CFP, PFC, Complement factor P

Aufreinigung: Affinity chromatography on Protein A

Immunogen: Native purified factor P from human serum.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA. Functional Assays. Immunohistochemistry on frozen sections. Recommended Positive Control: Kidney from post streptoccal glomerulonephritis patients.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Borate buffered saline pH 8.2 containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CFP

Target: CFP (Complement Factor P (CFP))

Andere Bezeichnung: Properdin

Hintergrund: Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.Synonyms: CFP, Complement factor P, PFC

Gen-ID: 5199

UniProt: P27918

Pathways: Komplementsystem