CFP Antikörper (AA 197-223)
Kurzübersicht für CFP Antikörper (AA 197-223) (ABIN3030563)
Target
Alle CFP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 197-223
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Verwendungszweck
- CFP Antibody / Complement Factor P / Properdin
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Aufreinigung
- Antigen affinity
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Immunogen
- A portion of amino acids 197-223 from the human protein was used as the immunogen for this CFP antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- Titration of the CFP antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the CFP antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- CFP (Complement Factor P (CFP))
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Andere Bezeichnung
- CFP
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Hintergrund
- This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
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UniProt
- P27918
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Pathways
- Komplementsystem
Target
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