CFP Antikörper (AA 197-223)

Produktnummer ABIN653898

Produktdetails anti-CFP Antikörper

Target: CFP (Complement Factor P (CFP))

Bindungsspezifität: AA 197-223

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CFP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CFP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-223 amino acids from the Central region of human CFP.

Klon: RB22181

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:500. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CFP

Target: CFP (Complement Factor P (CFP))

Andere Bezeichnung: CFP (CFP Produkte)

Synonyme: BFD antikoerper, PFC antikoerper, PFD antikoerper, PROPERDIN antikoerper, BCFG antikoerper, Pfc antikoerper, Properdin antikoerper, complement factor properdin antikoerper, CFP antikoerper, Cfp antikoerper

Hintergrund: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.

Molekulargewicht: 51276

Gen-ID: 5199

NCBI Accession: NP_001138724, NP_002612

UniProt: P27918

Pathways: Komplementsystem