BCL10 Antikörper (N-Term)

Produktnummer ABIN1732247

Der Kaninchen Polyklonal anti-BCL10 Antikörper wird verwendet zum Nachweis von BCL10 in Proben von Human. Er wurde validiert für WB, IF, ICC und IHC (p).

Kurzübersicht für BCL10 Antikörper (N-Term) (ABIN1732247)

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BCL10 Antikörper

Bindungsspezifität: AA 5-19, N-Term

Spezifität: Reacts with human Bcl-10.

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to aa 5-19 (N-terminus ) of human Bcl-10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC-P (10 μg/mL) WB(1 μg/mL) ICC(1 μg/mL)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BCL10

Target: BCL10 (B-Cell CLL/lymphoma 10 (BCL10))

Andere Bezeichnung: Bcl-10

Hintergrund: Overexpression of Bcl10 induces JNK, p38, and NF- B activation. Bcl10 interacts with caspase- 9, enhances pro-caspase-9 processing, and induces apoptosis through caspase-9 activation. Bcl10 exhibits a variety of mutations in MALT lymphoma and in B and T cell lymphomas indicating that it may be commonly involved in the pathogenesis of human tumors. Bcl10 is expressed in many human and murine tissues and cell lines.

B-cell lymphoma/leukemia 10 B-cell CLL/lymphoma 10, Bcl-10 CARD-containing molecule enhancing NF-kappa-B CARD-like apoptotic protein, hCLAP CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER Cellular homolog of vCARMEN, cCARMEN Cellular-E10, c-E10 Mammalian CARD-containing adapter molecule E10, mE10 Gene name: BCL10, CARMEN, CIPER, CLAP, IMD37

Gen-ID: 8915

UniProt: O95999

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine