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GLUT4 Antikörper (AA 224-353)

SLC2A4 Reaktivität: Human WB, IHC, ELISA, ICC, FACS Wirt: Maus Monoclonal 3G10A3 unconjugated
Produktnummer ABIN1724743
  • Target Alle GLUT4 (SLC2A4) Antikörper anzeigen
    GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
    Bindungsspezifität
    • 8
    • 6
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 224-353
    Reaktivität
    • 66
    • 48
    • 33
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 55
    • 17
    • 2
    Maus
    Klonalität
    • 57
    • 17
    Monoklonal
    Konjugat
    • 45
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Dieser GLUT4 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 27
    • 27
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Verwendungszweck
    SLC2A4 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human SLC2A4 (AA: 224-353 ) expressed in E. Coli.
    Klon
    3G10A3
    Isotyp
    IgG2b
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Sano, Peck, Kettenbach, Gerber, Lienhard: "Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C." in: The Journal of biological chemistry, Vol. 286, Issue 19, pp. 16541-5, (2011) (PubMed).

  • Target
    GLUT4 (SLC2A4) (Solute Carrier Family 2 (Facilitated Glucose Transporter), Member 4 (SLC2A4))
    Andere Bezeichnung
    SLC2A4 (SLC2A4 Produkte)
    Hintergrund

    Description: This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM).


    Aliases: GLUT4

    Molekulargewicht
    54.8kDa
    Gen-ID
    6517
    HGNC
    6517
    UniProt
    P14672
    Pathways
    AMPK Signaling, Carbohydrate Homeostasis, Proton Transport, Brown Fat Cell Differentiation, Warburg Effekt
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