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Survivin Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Survivin in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.
Produktnummer ABIN1724686

Kurzübersicht für Survivin Antikörper (ABIN1724686)

Target

Alle Survivin (BIRC5) Antikörper anzeigen
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Reaktivität

  • 131
  • 58
  • 48
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 100
  • 41
  • 1
  • 1
Maus

Klonalität

  • 95
  • 48
Monoklonal

Konjugat

  • 82
  • 12
  • 12
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Survivin Antikörper ist unkonjugiert

Applikation

  • 112
  • 56
  • 45
  • 42
  • 26
  • 26
  • 24
  • 20
  • 14
  • 13
  • 7
  • 6
  • 5
  • 3
  • 1
  • 1
  • 1
  • 1
ELISA

Klon

2H5H2
  • Verwendungszweck

    Survivin Antibody

    Aufreinigung

    Ascitic fluid

    Immunogen

    Purified recombinant fragment of Survivin expressed in E. Coli.

    Isotyp

    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Ascitic fluid containing 0.03 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Karam, Lotan, Ashfaq, Sagalowsky, Shariat: "Survivin expression in patients with non-muscle-invasive urothelial cell carcinoma of the bladder." in: Urology, Vol. 70, Issue 3, pp. 482-6, (2007) (PubMed).

    Piras, Murtas, Minerba, Ugalde, Floris, Maxia, Colombari, Perra, Sirigu: "Nuclear survivin is associated with disease recurrence and poor survival in patients with cutaneous malignant melanoma." in: Histopathology, Vol. 50, Issue 7, pp. 835-42, (2007) (PubMed).

  • Target

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    Andere Bezeichnung

    Survivin

    Hintergrund

    Baculoviral IAP repeat-containing 5 (survivin). This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

    Gen-ID

    332

    UniProt

    O15392

    Pathways

    Apoptose, Zellzyklus, Nuclear Hormone Receptor Binding
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