IL1A Antikörper

Produktnummer ABIN1724632

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL1A in ELISA. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für IL1A Antikörper (ABIN1724632)

Target: IL1A (Interleukin 1 alpha (IL1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL1A Antikörper ist unkonjugiert

Applikation: ELISA

Klon: 3A6F11

Produktdetails anti-IL1A Antikörper

Verwendungszweck: IL-1a Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human IL1a expressed in E. Coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-IL1A Antikörper (ABIN1724632)

Grimaldi, Casadei, Ferri, Veglia, Licastro, Annoni, Biunno, De Bellis, Sorbi, Mariani, Canal, Griffin, Franceschi: "Association of early-onset Alzheimer's disease with an interleukin-1alpha gene polymorphism." in: Annals of neurology, Vol. 47, Issue 3, pp. 361-5, (2000) (PubMed).

Du, Dodel, Eastwood, Bales, Gao, Lohmüller, Müller, Kurz, Zimmer, Evans, Hake, Gasser, Oertel, Griffin, Paul, Farlow: "Association of an interleukin 1 alpha polymorphism with Alzheimer's disease." in: Neurology, Vol. 55, Issue 4, pp. 480-3, (2000) (PubMed).

Details zu IL1A

Target: IL1A (Interleukin 1 alpha (IL1A))

Andere Bezeichnung: IL-1a

Hintergrund: Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease

Molekulargewicht: 30.6 kDa

Gen-ID: 3552

UniProt: P01583

Pathways: NF-kappaB Signalweg, Autophagie, Cancer Immune Checkpoints