IL-6 Receptor Antikörper

Produktnummer ABIN1722534

Produktdetails anti-IL-6 Receptor Antikörper

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Functional Studies (Func)

Spezifität: Reacts with human interleukin-6 Receptor α subunit, IL-6 Ra, IL-6 R, a 80 kDa protein

Kreuzreaktivität (Details): Recognizes both soluble and membrane bound IL-6 R

Aufreinigung: Purified

Immunogen: CD126/gp80 transfected CHO cell line

Klon: B-F19

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

Working dilution: Blocks IL-6 induced proliferation of XG-1 cell line Blocks IL-6 binding to its receptor
IHC, WB : not tested

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: PBS. Sterile-filtered through 0.22 μm and treated to remove endotoxins. Carrier and preservative free, Azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C

Informationen zur Lagerung: Stable at +2-8°C for 12 months For longer storage, freeze aliquots

Haltbarkeit: 12 months

Details zu IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Andere Bezeichnung: CD126 / IL-6R (IL6R Produkte)

Hintergrund: CD126 is the alpha subunit of IL-6 receptor and needs to be associated to IL6ST to transduce signals.

Gen-ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints