BCL3 Antikörper

Produktnummer ABIN1721461

Dieser Hamster Monoklonal Antikörper detektiert spezifisch BCL3 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für BCL3 Antikörper (ABIN1721461)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Human, Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 150-3-5

Produktdetails anti-BCL3 Antikörper

Spezifität: Reacts with human and mouse Bcl-3.

Aufreinigung: Purified

Immunogen: Recombinant mouse Bcl-3-6His.

Isotyp: IgG1 lambda

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB2 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: Bcl-3

Hintergrund: The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IκB subfamily of inhibitors of NFκB transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NFκB1 and NFκB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFκB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.

B-cell lymphoma 3 protein homolog, BCL-3 Gene name: Bcl3

UniProt: Q9Z2F6

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus