BCL3 Antikörper

Produktnummer ABIN1721461

Dieses Hamster Monoklonal-Antikörper erkennt spezifisch BCL3 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für BCL3 Antikörper (ABIN1721461)

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Reaktivität: Human, Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser BCL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Klon: 150-3-5

Produktdetails anti-BCL3 Antikörper

Spezifität: Reacts with human and mouse Bcl-3.

Aufreinigung: Purified

Immunogen: Recombinant mouse Bcl-3-6His.

Isotyp: IgG1 lambda

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB2 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.4

Handhabung: Dilute in PBS or medium that is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BCL3

Target: BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

Andere Bezeichnung: Bcl-3

Hintergrund: The gene encoding Bcl-3 was first identified as the gene altered in some cases of chronic B cell lymphocytic leukemia and was later found to belong to the IκB subfamily of inhibitors of NFκB transcription factors. Bcl-3 does not have DNA-binding activity, but it interacts with NFκB1 and NFκB2 which, when bound to DNA, repress gene transcription. Therefore, Bcl-3 may promote gene expression that is repressed by members of the NFκB family. Bcl-3 RNA is highly expressed in spleen and liver with lower levels of expression in heart, skeletal muscle, lung, kidney, and testes.

B-cell lymphoma 3 protein homolog, BCL-3 Gene name: Bcl3

UniProt: Q9Z2F6

Pathways: NF-kappaB Signalweg, Maintenance of Protein Location, Protein targeting to Nucleus