Caspase 6 Antikörper (AA 181-293)
Kurzübersicht für Caspase 6 Antikörper (AA 181-293) (ABIN1714708)
Target
Alle Caspase 6 (CASP6) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 181-293
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Verwendungszweck
- Caspase-6 subunit p11 Antibody
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Kreuzreaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio)
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Homologie
- Dog,Cow,Pig
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human Caspase-6 subunit p11
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Isotyp
- IgG
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Applikationshinweise
- WB(1:300-5000),
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- Caspase 6 (CASP6) (Caspase 6, Apoptosis-Related Cysteine Peptidase (CASP6))
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Andere Bezeichnung
- Caspase-6
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Hintergrund
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Synonyms: Caspase-6 subunit p11, Caspase-6 p11, Apoptosis Related Cysteine Protease, Apoptotic cysteine protease MCH2, Apoptotic protease MCH 2, Apoptotic protease MCH2, Casp 6, Casp6, Caspase 6 apoptosis related cysteine protease, Caspase 6 precursor, Caspase6, Human cysteine protease Mch2 isoform alpha, Mch 2, Mch2, CASP6_HUMAN.
Background: Caspase-6 Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death. Subunit is compose of heterodimer of a18 kDa (p18) and a 11 kDa (p11) subunit. Subcellular location at cytoplasmic. Cleavages by CPP32, caspase-8 or -10 generate the two active subunits. It belongs to the peptidase C14 family.
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Gen-ID
- 839
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UniProt
- P55212
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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