ABL1 Antikörper (C-Abl Oncogene 1, Non-Receptor tyrosine Kinase) (pThr754) (Cy5)

Details for Product anti-ABL1 Antibody No. ABIN1705044
Antigen
  • ABL
  • JTK7
  • bcr/abl
  • c-ABL
  • p150
  • v-abl
  • AI325092
  • Abl
  • E430008G22Rik
  • c-Abl
  • ABL proto-oncogene 1, non-receptor tyrosine kinase
  • c-abl oncogene 1, non-receptor tyrosine kinase
  • Tyrosine-protein kinase abl-1
  • ABL1
  • Abl1
  • abl-1
  • abl1
Epitop
pThr754, pThr735
62
57
49
46
24
20
18
18
16
16
16
15
15
15
15
15
15
15
15
12
12
11
11
8
8
7
7
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
629
402
328
22
7
1
1
1
1
Wirt
Kaninchen
635
15
Klonalität
Polyklonal
Konjugat
Dieser ABL1 Antikörper ist konjugiert mit Cy5
35
29
28
19
19
19
19
19
18
16
16
16
14
14
14
14
14
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
371
220
207
181
100
64
46
19
17
12
6
2
2
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human c-Abl isoform b around the phosphorylation site of Thr754
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere ABL1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung C-Abl (ABL1 Antibody Abstract)
Hintergrund

The c Abl proto oncogene encodes a protein tyrosine kinase that is located in the cytoplasm and nucleus. In chronic myelogenous leukemia and in a subset of acute lymphoblastic leukemias, the c Abl proto oncogene undergoes a (9,22) chromosomal translocation producing a novel rearranged chromosome (the Philadelphia chromosome) As the result of the fusion of c Abl sequences from chromosome 9 to the Bcr gene on chromosome 22. The molecular consequence of this translocation is the generation of a chimeric Bcr/Abl mRNA encoding activated Abl protein tyrosine kinase.

Synonyms: c-AblThr754/Thr735, Abelson Murine Leukemia Viral Oncogene Homolog 1, Abelson murine leukemia viral v abl oncogene homolog 1, Abl 1, ABL, Abl protein, Abl1, Bcr/c abl oncogene protein, JTK 7, JTK7, p150, Proto oncogene tyrosine protein kinase ABL1, Transformation gene oncogene ABL, v abl Abelson murine leukemia viral oncogene homolog 1, v abl, ABL1_HUMAN.

Gen-ID 25
Pathways Apoptose, Regulation of Muscle Cell Differentiation, Platelet-derived growth Factor Receptor Signaling, Lipid Metabolism
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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