TYROBP Antikörper (TYRO Protein tyrosine Kinase Binding Protein) (Cy5)

Details for Product anti-TYROBP Antibody No. ABIN1704844
Antigen
  • TYROBP
  • DAP12
  • tyrpbp
  • Karap
  • KARAP
  • PLOSL
  • Ly83
  • dap12
  • TYRO protein tyrosine kinase binding protein
  • Tyro protein tyrosine kinase binding protein
  • TYROBP
  • tyrobp
  • Tyrobp
Reaktivität
Human, Maus, Ratte (Rattus)
91
27
25
1
1
1
1
Wirt
Kaninchen
95
5
1
Klonalität
Polyklonal
Konjugat
Dieser TYROBP Antikörper ist konjugiert mit Cy5
6
4
4
4
4
4
4
4
3
2
2
2
2
2
2
2
2
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
53
29
25
21
19
16
4
2
2
Optionen
Immunogen KLH conjugated synthetic peptide derived from human DAP12
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere TYROBP products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Dap12 (TYROBP Antibody Abstract)
Hintergrund

This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

Synonyms: DAP 12, DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP.

Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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