Cyclin D3 Antikörper (CCND3) (pThr283) (Cy5)

Details for Product anti-CCND3 Antibody No. ABIN1704372
Antigen
  • zgc:103502
  • CCND3
  • 9230106B05Rik
  • AA682053
  • AL024085
  • AW146355
  • C78795
  • cyclin D3
  • ccnd3
  • CCND3
  • Ccnd3
Epitop
pThr283
50
42
24
17
15
10
8
3
3
3
2
2
2
2
2
2
2
1
Reaktivität
Human, Maus, Ratte (Rattus)
227
153
135
10
5
4
3
2
1
1
1
1
Wirt
Kaninchen
203
44
Klonalität
Polyklonal
Konjugat
Dieser Cyclin D3 Antikörper ist konjugiert mit Cy5
12
8
8
6
6
6
5
5
5
5
5
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
161
85
62
36
25
19
19
14
12
8
5
2
1
1
1
1
1
1
1
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human Cyclin D3 around the phosphorylation site of Thr283
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere Cyclin D3 products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Cyclin D3 (CCND3 Antibody Abstract)
Hintergrund

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

Synonyms: Cyclin D3 phospho T283, Cyclin D3 phospho Thr283, p-Cyclin D3 T283, p-Cyclin D3 Thr283, p-Cyclin D3 phospho T283, CCND 3, Ccnd3, CCND3_HUMAN, CyclinD3, D3 type cyclin, G1 S specic cyclin D3, G1/S specic cyclin D3, G1/S-specic cyclin-D3.

Gen-ID 896
Pathways Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months