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FAK Antikörper (pTyr576) (Cy5)

PTK2 Reaktivität: Maus WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Cy5
Produktnummer ABIN1704203
  • Target Alle FAK (PTK2) Antikörper anzeigen
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Bindungsspezifität
    • 43
    • 34
    • 30
    • 28
    • 23
    • 22
    • 22
    • 21
    • 16
    • 16
    • 13
    • 11
    • 7
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr576
    Reaktivität
    • 332
    • 278
    • 209
    • 22
    • 21
    • 17
    • 16
    • 12
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 336
    • 20
    • 3
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 330
    • 33
    Polyklonal
    Konjugat
    • 158
    • 17
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 1
    • 1
    Dieser FAK Antikörper ist konjugiert mit Cy5
    Applikation
    • 292
    • 133
    • 133
    • 120
    • 106
    • 68
    • 61
    • 42
    • 31
    • 29
    • 23
    • 5
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Maus
    Homologie
    Human,Rat,Dog,Cow,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr576
    Isotyp
    IgG
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  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    Andere Bezeichnung
    FAK (PTK2 Produkte)
    Hintergrund

    Synonyms: FAK phospho Y576, p-FAK phospho Y576, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.

    Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.

    Gen-ID
    5747
    Pathways
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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