FAK Antikörper (PTK2 Protein tyrosine Kinase 2) (pTyr576) (Cy5)

Details for Product anti-PTK2 Antibody No. ABIN1704203
Antigen
  • FADK
  • FAK
  • FAK1
  • FRNK
  • PPP1R71
  • p125FAK
  • pp125FAK
  • PTK2
  • Fadk
  • mKIAA4203
  • fak
  • fak1a
  • ptk2
  • ptk2a
  • wu:fa18c04
  • zgc:66114
  • CG10023
  • CT28129
  • DFAK
  • DFak
  • DFak56
  • Dfak
  • Dfak56
  • DmFAK
  • Dmel\\CG10023
  • Fak56
  • Fak56D
  • fak56
  • protein tyrosine kinase 2
  • protein tyrosine kinase 2 L homeolog
  • PTK2 protein tyrosine kinase 2
  • protein tyrosine kinase 2ab
  • Focal adhesion kinase
  • PTK2
  • ptk2.L
  • Ptk2
  • ptk2ab
  • Fak
Epitop
pTyr576
91
71
70
57
53
31
31
27
21
21
19
17
16
15
15
9
9
8
7
7
6
5
5
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
790
547
528
44
27
24
14
10
9
8
7
3
3
3
3
3
3
2
1
1
Wirt
Kaninchen
741
78
3
2
1
1
Klonalität
Polyklonal
Konjugat
Dieser FAK Antikörper ist konjugiert mit Cy5
30
23
23
23
23
22
22
17
17
11
11
11
11
10
5
2
2
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
551
253
199
144
140
104
62
35
29
18
9
6
3
3
2
Optionen
Immunogen KLH conjugated synthetic phosphopeptide derived from human PTK2 around the phosphorylation site of Tyr576
Isotyp IgG
Reinigung Purified by Protein A.
Plasmids, Primers & others Plasmide, Primers & weitere FAK products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Fak (PTK2 Antibody Abstract)
Hintergrund

Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.

Synonyms: FAK phospho Y576, p-FAK phospho Y576, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.

Gen-ID 5747
Pathways Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
Applikations-hinweise IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store at 4°C
Haltbarkeit 12 months
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