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FAK Antikörper (AA 700-800)
PTK2
Reaktivität: Human
WB, IHC, IF, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN6146423
Produktdetails anti-FAK Antikörper
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Target
Alle FAK (PTK2) Antikörper anzeigen
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Bindungsspezifität
Alle Epitope für FAK Antikörper
AA 700-800
Reaktivität
Alle Reaktivitäten für FAK Antikörper
Human
Wirt
Alle Wirte für FAK Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für FAK Antikörper
Polyklonal
Konjugat
Alle Konjugate für FAK Antikörper
Dieser FAK Antikörper ist unkonjugiert
Applikation
Alle Applikationen für FAK Antikörper
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
Sequenz
TVSWDSGGSD EAPPKPSRPG YPSPRSSEGF YPSPQHMVQT NHYQVSGYPG SHGITAMAGS IYPGQASLLD QTDSWNHRPQ EIAMWQPNVE DSTVLDLRGI G
Kreuzreaktivität
Human, Maus, Ratte
Produktmerkmale
Polyclonal Antibodies
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human FAK (NP_722560.1).
Isotyp
IgG
Top Product
Discover our top product PTK2 Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:100
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-FAK Antikörper (ABIN6146423)
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Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou : "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP. " in: FEBS letters , Vol. 592 , Issue 4 , pp. 599-609 , (2019 ) (PubMed ).
Details zu FAK
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Target
FAK (PTK2)
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Andere Bezeichnung
PTK2 (PTK2 Produkte )
Synonyme
FADK antikoerper, FAK antikoerper, FAK1 antikoerper, FRNK antikoerper, PPP1R71 antikoerper, p125FAK antikoerper, pp125FAK antikoerper, PTK2 antikoerper, Fadk antikoerper, mKIAA4203 antikoerper, fak antikoerper, fak1a antikoerper, ptk2 antikoerper, ptk2a antikoerper, wu:fa18c04 antikoerper, zgc:66114 antikoerper, CG10023 antikoerper, CT28129 antikoerper, DFAK antikoerper, DFak antikoerper, DFak56 antikoerper, Dfak antikoerper, Dfak56 antikoerper, DmFAK antikoerper, Dmel\\CG10023 antikoerper, Fak56 antikoerper, Fak56D antikoerper, fak56 antikoerper, protein tyrosine kinase 2 antikoerper, protein tyrosine kinase 2 L homeolog antikoerper, PTK2 protein tyrosine kinase 2 antikoerper, protein tyrosine kinase 2ab antikoerper, Focal adhesion kinase antikoerper, PTK2 antikoerper, ptk2.L antikoerper, Ptk2 antikoerper, ptk2ab antikoerper, Fak antikoerper
Hintergrund
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.,FADK,FAK,FAK1,FRNK,PPP1R71,p125FAK,pp125FAK,PTK2,Cancer,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Tyrosine kinases,PI3K-Akt Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Actins,Extracellular Matrix,Immunology & Inflammation,Cardiovascular,Angiogenesis,PTK2
Molekulargewicht
39 kDa/48 kDa/63 kDa/99 kDa/114 kDa/119 kDa/120 kDa
Gen-ID
5747
UniProt
Q05397
Pathways
Response to Growth Hormone Stimulus , CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Signaling of Hepatocyte Growth Factor Receptor , VEGF Signaling
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