FAK Produkte
(PTK2 Protein tyrosine Kinase 2 (PTK2))
Kategorien
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. [provided by RefSeq, Dec 2010].
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Ausgewählte FAK Kategorien
FAK Antikörper
High quality antibodies with extensive validation data.
FAK ELISA Kits
Reliable ELISA kits for a wide range of species.
FAK Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FAK Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (3)
- (8)
Kat. Nr.
ABIN6256730
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF, IP
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN6146423
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (7)
Kat. Nr.
ABIN7439699
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FAK ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6958990
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6969779
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962403
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FAK Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (2)
Kat. Nr.
ABIN1316775
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf21)
Validierungen
- (2)
Kat. Nr.
ABIN5570573
Menge
5 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Insect cells (Sf9)
Validierungen
- (2)
Kat. Nr.
ABIN5569839
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FAK Produkten
: "Role and Regulation of Mechanotransductive HIF-1α Stabilisation in Periodontal Ligament Fibroblasts." in: International journal of molecular sciences, Vol. 21, Issue 24, (2021) (PubMed).: "Phosphorylation of EphA2 receptor and vasculogenic mimicry is an indicator of poor prognosis in invasive carcinoma of the breast." in: Breast cancer research and treatment, Vol. 179, Issue 2, pp. 359-370, (2020) (PubMed).
: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).
: "Porcine Breast Extracellular Matrix Hydrogel for Spatial Tissue Culture." in: International journal of molecular sciences, Vol. 19, Issue 10, (2019) (PubMed).
: "Depletion of transglutaminase 2 in neurons alters expression of extracellular matrix and signal transduction genes and compromises cell viability." in: Molecular and cellular neurosciences, Vol. 86, pp. 72-80, (2018) (PubMed).
: "Down-regulating Myoferlin inhibits the vasculogenic mimicry of melanoma via decreasing MMP-2 and inducing mesenchymal-to-epithelial transition." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1743-1754, (2018) (PubMed).
: "MFAP5 promotes tumor progression and bone metastasis by regulating ERK/MMP signaling pathways in breast cancer." in: Biochemical and biophysical research communications, Vol. 498, Issue 3, pp. 495-501, (2018) (PubMed).
: "Ovostatin 2 knockdown significantly inhibits the growth, migration, and tumorigenicity of cutaneous malignant melanoma cells." in: PLoS ONE, Vol. 13, Issue 4, pp. e0195610, (2018) (PubMed).
: "Picornavirus 2A protease regulates stress granule formation to facilitate viral translation." in: PLoS pathogens, Vol. 14, Issue 2, pp. e1006901, (2018) (PubMed).
: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).
Synonyme und alternative Namen zu FAK
protein tyrosine kinase 2 (PTK2), protein tyrosine kinase 2 L homeolog (ptk2.L), PTK2 protein tyrosine kinase 2 (PTK2), PTK2 protein tyrosine kinase 2 (Ptk2), protein tyrosine kinase 2ab (ptk2ab), protein tyrosine kinase 2 (Ptk2), Focal adhesion kinase (Fak), CG10023, CT28129, DFAK, DFak, Dfak, DFak56, Dfak56, Dmel\\CG10023, DmFAK, FADK, Fadk, FAK, fak, FAK1, fak1a, Fak56, fak56, Fak56D, FRNK, mKIAA4203, p125FAK, pp125FAK, PPP1R71, PTK2, ptk2, ptk2a, wu:fa18c04, zgc:66114Bezeichner auf Proteinebene für FAK
- FADK 1
- FAK-related non-kinase polypeptide
- PTK2 protein tyrosine kinase 2
- focal adhesion kinase 1
- focal adhesion kinase-related nonkinase
- protein phosphatase 1 regulatory subunit 71
- protein phosphatase 1, regulatory subunit 71
- focal adhesion kinase pp125FAK
- pp125FAK
- protein-tyrosine kinase 2
- focal adhesion kinase
- focal ashension kinase 1
- p41/p43FRNK
- faka
- protein tyrosine kinase 2.1
- CG10023-PA
- CG10023-PB
- CG10023-PC
- CG10023-PD
- CG10023-PF
- CG10023-PG
- Fak-PA
- Fak-PB
- Fak-PC
- Fak-PD
- Fak-PF
- Fak-PG
- focal adhesion kinase homolog
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