ZYX Antikörper

Produktnummer ABIN1682627

Der Kaninchen Monoklonal anti-ZYX Antikörper wird verwendet zum Nachweis von ZYX in Proben von Human. Er wurde validiert für WB und IF.

Kurzübersicht für ZYX Antikörper (ABIN1682627)

Target: ZYX (Zyxin (ZYX))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ZYX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-ZYX Antikörper

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Zyxin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZYX

Target: ZYX (Zyxin (ZYX))

Andere Bezeichnung: ZYX

Hintergrund: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008],ESP-2, HED-2,Cell Adhesion,Cell Biology & Developmental Biology,Cytoskeleton,Cytoskeleton_Microfilaments,Epigenetics & Nuclear Signaling,Neuroscience,RNA Binding,Signal Transduction,Transcription Factors,ZYX

Molekulargewicht: 78 kDa

Gen-ID: 7791

UniProt: Q15942