ZYX Antikörper (AA 1-300)

Produktnummer ABIN3023009

Produktdetails anti-ZYX Antikörper

Target: ZYX (Zyxin (ZYX))

Bindungsspezifität: AA 1-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZYX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MAAPRPSPAI SVSVSAPAFY APQKKFGPVV APKPKVNPFR PGDSEPPPAP GAQRAQMGRV GEIPPPPPED FPLPPPPLAG DGDDAEGALG GAFPPPPPPI EESFPPAPLE EEIFPSPPPP PEEEGGPEAP IPPPPQPREK VSSIDLEIDS LSSLLDDMTK NDPFKARVSS GYVPPPVATP FSSKSSTKPA AGGTAPLPPW KSPSSSQPLP QVPAPAQSQT QFHVQPQPQP KPQVQLHVQS QTQPVSLANT QPRGPPASSP APAPKFSPVT PKFTPVASKF SPGAPGGSGS QPNQKLGHPE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Zyxinin (NP_001010972.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZYX

Target: ZYX (Zyxin (ZYX))

Andere Bezeichnung: ZYX (ZYX Produkte)

Synonyme: BcDNA:LD06023 antikoerper, CG32018 antikoerper, DLim-1 antikoerper, DmLIM-1 antikoerper, Dmel\\CG32018 antikoerper, Lim102EF antikoerper, ZYX102 antikoerper, Zyx102 antikoerper, Zyx102EF antikoerper, lim antikoerper, zyx102 antikoerper, zyxin antikoerper, zgc:171680 antikoerper, ZYX antikoerper, zyx antikoerper, MGC145270 antikoerper, ESP-2 antikoerper, HED-2 antikoerper, 9530098H06Rik antikoerper, R75157 antikoerper, Zyxin antikoerper, zyxin antikoerper, zyxin S homeolog antikoerper, zyx-1 antikoerper, Zyx antikoerper, zyx antikoerper, ZYX antikoerper, EDI_201420 antikoerper, zyx.S antikoerper

Hintergrund: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.,ZYX,ESP-2,HED-2,zyxin,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Microfilaments,Neuroscience,ZYX

Molekulargewicht: 45 kDa/61 kDa

Gen-ID: 7791

UniProt: Q15942