ZYX Antikörper

Produktnummer ABIN7260207

Produktdetails anti-ZYX Antikörper

Target: ZYX (Zyxin (ZYX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZYX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein of human ZYX (NP_001010972.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000 IHC 1:50-1:200 IF 1:50-1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZYX

Target: ZYX (Zyxin (ZYX))

Andere Bezeichnung: ZYX (ZYX Produkte)

Synonyme: BcDNA:LD06023 antikoerper, CG32018 antikoerper, DLim-1 antikoerper, DmLIM-1 antikoerper, Dmel\\CG32018 antikoerper, Lim102EF antikoerper, ZYX102 antikoerper, Zyx102 antikoerper, Zyx102EF antikoerper, lim antikoerper, zyx102 antikoerper, zyxin antikoerper, zgc:171680 antikoerper, ZYX antikoerper, zyx antikoerper, MGC145270 antikoerper, ESP-2 antikoerper, HED-2 antikoerper, 9530098H06Rik antikoerper, R75157 antikoerper, Zyxin antikoerper, zyxin antikoerper, zyxin S homeolog antikoerper, zyx-1 antikoerper, Zyx antikoerper, zyx antikoerper, ZYX antikoerper, EDI_201420 antikoerper, zyx.S antikoerper

Hintergrund: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform.

Molekulargewicht:

Observed_MW: 78 kDa

Calculated_MW: 45 kDa/61 kDa

Gen-ID: 7791

UniProt: Q15942