ZYX Antikörper (Middle Region)
Kurzübersicht für ZYX Antikörper (Middle Region) (ABIN2775766)
Target
Alle ZYX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- ZYX Antibody - middle region
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Sequenz
- GSPQPPSFTY AQQREKPRVQ EKQHPVPPPA QNQNQVRSPG APGPLTLKEV
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Homologie
- Cow: 85%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 91%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ZYX. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ZYX
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34387-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1.0 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "A zyxin head-tail interaction regulates zyxin-VASP complex formation." in: Biochemical and biophysical research communications, Vol. 378, Issue 3, pp. 625-8, (2008) (PubMed).
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- ZYX (Zyxin (ZYX))
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Andere Bezeichnung
- ZYX
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Hintergrund
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Background Information: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Gene Name: Zyxin
Alternative Symbols: ESP-2, HED-2
Protein Name: Zyxin
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Molekulargewicht
- 61kDa
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Gen-ID
- 7791
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NCBI Accession
- NP_003452
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UniProt
- Q15942
Target
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