FLT4 Antikörper
-
- Target Alle FLT4 Antikörper anzeigen
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser FLT4 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Spezifität
- Recombinant human sFLT-4 (D1-7)
- Produktmerkmale
-
Chromosomal location: 5q35.3
Produced from sera of rabbits immunised with highly pure recombinant human soluble VEGFR-3/FLT-4 (D1-D7). - Aufreinigung
- Anti-human VEGFR-3/FLT-4 was purified by antigen-affinity chromatography with immobilised soluble VEGFR-3/FLT-4.
- Isotyp
- IgG
- Top Product
- Discover our top product FLT4 Primärantikörper
-
-
- Applikationshinweise
- Western Blot: use 1-5 µg/mL
- Kommentare
-
Rabbit IG Polyclonal Antibody
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Lyophilized
- Rekonstitution
- Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.
- Buffer
- PBS
- Handhabung
- Centrifuge vial prior to opening.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The lyophilized antibody is stable at room temperature for up to 1 month. The reconstituted antibody is stable for at least two weeks at 2-8 °C. Frozen aliquots are stable for at least 6 months when stored at -20 °C.
- Haltbarkeit
- 6 months
-
-
The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia." in: Placenta, Vol. 36, Issue 3, pp. 279-86, (2015) (PubMed).
: "
-
The defect of both angiogenesis and lymphangiogenesis is involved in preeclampsia." in: Placenta, Vol. 36, Issue 3, pp. 279-86, (2015) (PubMed).
-
- Target
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
- Andere Bezeichnung
- VEGFR-3/FLT-4 (FLT4 Produkte)
- Synonyme
- FLT41 antikoerper, LMPH1A antikoerper, PCL antikoerper, VEGFR3 antikoerper, AI323512 antikoerper, Chy antikoerper, Flt-4 antikoerper, VEGFR-3 antikoerper, Vegfr3 antikoerper, cb1059 antikoerper, fms related tyrosine kinase 4 antikoerper, FMS-like tyrosine kinase 4 antikoerper, fms-related tyrosine kinase 4 antikoerper, FLT4 antikoerper, Flt4 antikoerper, flt4 antikoerper
- Hintergrund
-
Receptor tyrosine Kinase VEGFR-3, also known as FLT4, together with VEGFR1 (FIT1) and VEGFR2 (KDR/Flk-1), are the receptors for vascular endothelial growth factors (VEGF). The VEGFR family belongs to the class II subfamily of receptor tyrosine kinases (RTKs), containing a large extracellular region which is composed of seven Ig-like domains (D1–D7), a single transmembrane (TM) helix and cytoplasmic region with a tyrosine kinase activity. In VEGFR-3, the fifth Ig homology domain is proteolytically cleaved which results in polypeptides remain linked by two disulfide bonds. VEGFR-3 is widely expressed on all endothelia cells in early embryogenesis, while, in adult tissues, VEGFR-3 expression disappears from the vascular endothelial cells and is observed only on the lymphatic endothelium. VEGF-C and VEGF-D activation of VEGFR-3 plays an important role in the formation of the lymphatic vessel system.
Synonyms: vascular endothelial growth factor receptor-3, FLT4, PCL, LMPH1A, VEGFR3, fms-related tyrosine kinase 4 - NCBI Accession
- NP_002011, NM_002020
- UniProt
- P35916
- Pathways
- RTK Signalweg, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
-