SF3B4 Antikörper

Produktnummer ABIN1580459

Der Maus Monoklonal Anti-SF3B4-Antikörper wurde für WB, IHC, IF und ICC validiert. Er ist geeignet, SF3B4 in Proben von Human, Maus, Ratte, Rind (Kuh), Schwein und Säugetier zu detektieren.

Kurzübersicht für SF3B4 Antikörper (ABIN1580459)

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Säugetier

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SF3B4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: 3A1

Produktdetails anti-SF3B4 Antikörper

Aufreinigung: affinity purified antibody

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: The antibody is affinity purified antibody diluted to 1mg/ml in phosphate buffered saline at a volume of 100 μl. The antibody solution can be used at dilutions of at least 1:1,000 in immunofluorescence experiments. In western blotting using chemiluminescence it can be used at dilutions of 1:1,000 or lower.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4°C short term or -20°C long term.

Details zu SF3B4

Target: SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

Hintergrund: SF3B4, also known as SAP49, is a ubiquitously expressed splicing factor found in the nuclei of eukaryotic cells, although it migrates into the cytoplasm of dividing cells. It was originally identified by as the protein most efficiently UV cross-linked to the A, B and C spliceosomal complexes. The protein contains two of the highly conserved RRM type RNA recognition motifs, each corresponding to a small approx. 70 amino acid structure, consisting of 4 beta strands and two alpha-helices. Proteins containing these proteins are believed to have a role in the regulation of mRNA splicing. The protein runs on SDS-PAGE gels at an apparent molecular weight of 49 kDa. This protein is known as splicing factor 3b, subunit 4, 49 kDa SAP49, spliceosome-associated protein (U2 snRNP), Hsh49 and MGC108282. Antibodies to this protein are good markers of nuclei. The HGNC name for this protein is SF3B4.