DDR2 Antikörper (AA 290-320)

Produktnummer ABIN1539910

Dieser Maus Monoklonal Antikörper detektiert spezifisch DDR2 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für DDR2 Antikörper (AA 290-320) (ABIN1539910)

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DDR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 484CT5-5-4

Produktdetails anti-DDR2 Antikörper

Bindungsspezifität: AA 290-320

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This DDR2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 290-320 amino acids from human DDR2.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: IHC: 1:200. WB: 1:100~1600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DDR2 Antibody(Ascites) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu DDR2

Target: DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))

Andere Bezeichnung: DDR2

Hintergrund: Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq].

Molekulargewicht: 96736

Gen-ID: 4921

NCBI Accession: NP_001014796, NP_006173

UniProt: Q16832

Pathways: RTK Signalweg