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DDR2 Antikörper (C-Term)

KO Validated DDR2 Reaktivität: Human WB, IHC (p), ICC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2855450
  • Target Alle DDR2 Antikörper anzeigen
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Bindungsspezifität
    • 9
    • 9
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 46
    • 25
    • 2
    • 1
    Human
    Wirt
    • 52
    • 7
    Kaninchen
    Klonalität
    • 53
    • 6
    Polyklonal
    Konjugat
    • 28
    • 6
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DDR2 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 39
    • 21
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to DDR2 (discoidin domain receptor tyrosine kinase 2)
    DDR2 antibody [C2C3], C-term
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human DDR2. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product DDR2 Primärantikörper
  • Applikationshinweise
    WB: 1:1000-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Validation: KO/KD, Overexpression

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.43 mg/mL
    Buffer
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DDR2 (Discoidin Domain Receptor tyrosine Kinase 2 (DDR2))
    Andere Bezeichnung
    discoidin domain receptor tyrosine kinase 2 (DDR2 Produkte)
    Synonyme
    MIG20a antikoerper, NTRKR3 antikoerper, TKT antikoerper, TYRO10 antikoerper, AW495251 antikoerper, Ntrkr3 antikoerper, tyro10 antikoerper, DDR2 antikoerper, Tyro10 antikoerper, ddr2 antikoerper, si:ch211-193c2.1 antikoerper, discoidin domain receptor tyrosine kinase 2 antikoerper, discoidin domain receptor family, member 2 antikoerper, discoidin domain receptor family, member 2, like antikoerper, DDR2 antikoerper, Ddr2 antikoerper, ddr2l antikoerper
    Hintergrund
    Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein.

    Cellular Localization: Membrane
    Molekulargewicht
    97 kDa
    Gen-ID
    4921
    UniProt
    Q16832
    Pathways
    RTK Signalweg
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