PDK4 Antikörper

Produktnummer ABIN1539836

Der Maus-Monoklonal Anti-PDK4-Antikörper wurde für WB validiert. Er ist geeignet zum Nachweis von PDK4 in Proben aus Human und Maus. }

Kurzübersicht für PDK4 Antikörper (ABIN1539836)

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: 345CT19-6-2

Produktdetails anti-PDK4 Antikörper

Aufreinigung: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: Purified His-tagged PDK4 protein(Fragment) was used to produced this monoclonal antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:500-1:1000. WB: 1:250

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: PDK4 Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu PDK4

Target: PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))

Andere Bezeichnung: PDK4

Hintergrund: This gene is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.

Molekulargewicht: 46469

Gen-ID: 5166

NCBI Accession: NP_002603

UniProt: Q16654

Pathways: PI3K-Akt Signalweg, Hedgehog Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt