BAX Antikörper (AA 41-90)
Kurzübersicht für BAX Antikörper (AA 41-90) (ABIN1532504)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 41-90
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Verwendungszweck
- Bax Antibody
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Spezifität
- Bax Polyclonal Antibody detects endogenous levels of Bax protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human BAX. AA range:41-90
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Isotyp
- IgG
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Applikationshinweise
- Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Bax
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Hintergrund
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Synonyms: BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4
Background: RB transcriptional corepressor 1(RB1) Homo sapiens The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008],
Gene Name: BAX
Protein Name: Apoptosis regulator BAX
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Molekulargewicht
- 21 kDa
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OMIM
- 600040
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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