BAX Antikörper (pSer184)
Kurzübersicht für BAX Antikörper (pSer184) (ABIN1532125)
Target
Alle BAX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 143-192, pSer184
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Spezifität
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Bax (Phospho-Ser184) Antibody detects endogenous levels of Bax only when phosphorylated at Ser184.
PhosphorylationH:S184 M:S184 R:S184
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Aufreinigung
- The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Ser184.
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Isotyp
- IgG
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Applikationshinweise
- IHC: 1:50~1:100 ELISA: 1:10000
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Kommentare
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Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable at -20°C for at least 1 year.
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Haltbarkeit
- 12 months
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: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).
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: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).
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- BAX (BCL2-Associated X Protein (BAX))
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Andere Bezeichnung
- Bax
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Hintergrund
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Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4
NCBI Gene Symbol: BAX
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Molekulargewicht
- 21 kDa
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Gen-ID
- 581
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OMIM
- 600040
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UniProt
- Q07812
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Pathways
- p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
Target
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