IRAK1 Antikörper (pSer376)
Kurzübersicht für IRAK1 Antikörper (pSer376) (ABIN1532050)
Target
Alle IRAK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 342-391, pSer376
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Verwendungszweck
- IRAK-1 (phospho Ser376) Antibody
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Spezifität
- Phospho-IRAK-1 (S376) Polyclonal Antibody detects endogenous levels of IRAK-1 protein only when phosphorylated at S376.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human IRAK1 around the phosphorylation site of Ser376. AA range:342-391
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Isotyp
- IgG
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Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- IRAK1 (Interleukin-1 Receptor-Associated Kinase 1 (IRAK1))
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Andere Bezeichnung
- IRAK1
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Hintergrund
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Synonyms: IRAK1, IRAK, Interleukin-1 receptor-associated kinase 1, IRAK-1
Background: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
Gene Name: IRAK1
Protein Name: Interleukin-1 receptor-associated kinase 1
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Molekulargewicht
- 76 kDa
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Gen-ID
- 3654
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OMIM
- 300283
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UniProt
- P51617
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Pathways
- NF-kappaB Signalweg, TLR Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
Target
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