CSNK1A1 Antikörper (pTyr321)
Kurzübersicht für CSNK1A1 Antikörper (pTyr321) (ABIN1531736)
Target
Alle CSNK1A1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 287-336, pTyr321
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Verwendungszweck
- Casein Kinase Iα (phospho Thr321) Antibody
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Spezifität
- Phospho-Casein Kinase Iα (Y321) Polyclonal Antibody detects endogenous levels of Casein Kinase Iα protein only when phosphorylated at Y321.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Reinheit
- > 95 %
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Immunogen
- The antiserum was produced against synthesized peptide derived from human Casein Kinase I alpha around the phosphorylation site of Tyr321. AA range:287-336
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Isotyp
- IgG
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Applikationshinweise
- WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C/1 year
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Haltbarkeit
- 12 months
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- CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))
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Andere Bezeichnung
- Casein Kinase I alpha
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Hintergrund
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Synonyms: CSNK1A1, Casein kinase I isoform alpha, CKI-alpha, CK1
Background: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,function:Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 on 'Ser-45'.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CK1 Ser/Thr protein kinase family. Casein kinase I subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Monomer. Interacts with the Axin complex.,
Gene Name: CSNK1A1
Protein Name: Casein kinase I isoform alpha
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Molekulargewicht
- 38 kDa
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Gen-ID
- 1452
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OMIM
- 600505
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UniProt
- P48729
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Pathways
- WNT Signalweg, Hedgehog Signalweg
Target
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