BAX Antikörper (pThr167)

Produktnummer ABIN1531490

Der Kaninchen Polyklonal Anti-BAX-Antikörper wurde für ELISA und IF validiert. Er ist geeignet, BAX in Proben von Human, Maus und Ratte zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für BAX Antikörper (pThr167) (ABIN1531490)

Target: BAX (BCL2-Associated X Protein (BAX))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAX Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-BAX Antikörper

Bindungsspezifität: AA 133-182, pThr167

Spezifität:

Bax (Phospho-Thr167) Antibody detects endogenous levels of Bax only when phosphorylated at Thr167.

PhosphorylationH:T167 M:T167 R:T167

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human Bax around the phosphorylation site of Thr167.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF: 1:100~1:500 ELISA: 1:40000

Kommentare:

Unigene-Number: Hs.433670, Hs.631546 (NCBI Gene Symbol: BAX)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Referenzen für anti-BAX Antikörper (ABIN1531490)

Grossini, Marotta, Farruggio, Sigaudo, Qoqaiche, Raina, de Giuli, Mary, Vacca, Pollastro: "Effects of Artemetin on Nitric Oxide Release and Protection against Peroxidative Injuries in Porcine Coronary Artery Endothelial Cells." in: Phytotherapy research : PTR, (2015) (PubMed).

Grossini, Bellofatto, Farruggio, Sigaudo, Marotta, Raina, De Giuli, Mary, Pollesello, Minisini, Pirisi, Vacca: "Levosimendan inhibits peroxidation in hepatocytes by modulating apoptosis/autophagy interplay." in: PLoS ONE, Vol. 10, Issue 4, pp. e0124742, (2015) (PubMed).

Grossini, Gramaglia, Farruggio, Bellofatto, Anchisi, Mary, Vacca, Zeppegno: "Asenapine increases nitric oxide release and protects porcine coronary artery endothelial cells against peroxidation." in: Vascular pharmacology, Vol. 60, Issue 3, pp. 127-41, (2014) (PubMed).

Grossini, Pollesello, Bellofatto, Sigaudo, Farruggio, Origlia, Mombello, Mary, Valente, Vacca: "Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats." in: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, Vol. 20, Issue 3, pp. 361-75, (2014) (PubMed).

Berger, Quast, Plötz, Kammermeier, Eberle: "Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax." in: Cell death & disease, Vol. 4, pp. e477, (2013) (PubMed).

Details zu BAX

Target: BAX (BCL2-Associated X Protein (BAX))

Andere Bezeichnung: Bax

Hintergrund:

Synonyms: Apoptosis regulator BAX, Bcl-2-like protein 4, Bcl2-L-4 , BAX , BCL2L4

NCBI Gene Symbol: BAX

Molekulargewicht: 21 kDa

Gen-ID: 581

OMIM: 600040

UniProt: Q07812

Pathways: p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response