SHP1 Antikörper (pTyr536)

Produktnummer ABIN1531195

Der Kaninchen Polyklonal Anti-SHP1-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, SHP1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für SHP1 Antikörper (pTyr536) (ABIN1531195)

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SHP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-SHP1 Antikörper

Bindungsspezifität: AA 502-551, pTyr536

Spezifität:

SHP-1 (Phospho-Tyr536) Antibody detects endogenous levels of SHP-1 only when phosphorylated at Tyr536.

PhosphorylationH:Y536 M:Y536 R:Y538

Aufreinigung: The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human SHP-1 around the phosphorylation site of Tyr536.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:10000

Kommentare:

Unigene-Number: Hs.63489 (NCBI Gene Symbol: PTPN6)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable at -20°C for at least 1 year.

Haltbarkeit: 12 months

Details zu SHP1

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Andere Bezeichnung: SHP-1

Hintergrund:

Synonyms: 70Z-SHP, HCP, HCPH, Hematopoietic cell protein-tyrosine phosphatase, PTN6, PTP-1C, PTP1C, PTPN6, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, Protein-tyrosine phosphatase, non-receptor type 6, SH-PTP1

NCBI Gene Symbol: PTPN6

Molekulargewicht: 67 kDa

Gen-ID: 5777

OMIM: 176883

UniProt: P29350

Pathways: JAK-STAT Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling