SETMAR Antikörper (AA 350-400)
Kurzübersicht für SETMAR Antikörper (AA 350-400) (ABIN1451979)
Target
Alle SETMAR Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 350-400
-
Verwendungszweck
- SETMAR Antibody
-
Spezifität
- SETMAR Polyclonal Antibody detects endogenous levels of SETMAR protein.
-
Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
Reinheit
- > 95 %
-
Immunogen
- The antiserum was produced against synthesized peptide derived from human SETMAR. AA range:350-400
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1 mg/mL
-
Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C/1 year
-
Haltbarkeit
- 12 months
-
-
- SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))
-
Andere Bezeichnung
- SETMAR
-
Hintergrund
-
Synonyms: SETMAR, Histone-lysine N-methyltransferase SETMAR, SET domain and mariner transposase fusion gene-containing protein, HsMar1, Metnase
Background: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
Gene Name: SETMAR
Protein Name: Histone-lysine N-methyltransferase SETMAR
-
Molekulargewicht
- 76 kDa
-
Gen-ID
- 6419
-
OMIM
- 609834
-
UniProt
- Q53H47
-
Pathways
- Positive Regulation of Response to DNA Damage Stimulus
Target
-