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TET2 Antikörper (N-Term)

TET2 Reaktivität: Human WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN1450172
  • Target Alle TET2 Antikörper anzeigen
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Bindungsspezifität
    • 16
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 47
    • 15
    • 6
    Human
    Wirt
    • 41
    • 8
    • 2
    Kaninchen
    Klonalität
    • 43
    • 8
    Polyklonal
    Konjugat
    • 33
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TET2 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 23
    • 11
    • 7
    • 7
    • 7
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human.
    Aufreinigung
    Affinity chromatography purified via peptide column
    Immunogen
    18 amino acid synthetic peptide near the amino terminus of Human TET2
    Isotyp
    IgG
    Top Product
    Discover our top product TET2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TET2 (Tet Methylcytosine Dioxygenase 2 (TET2))
    Andere Bezeichnung
    TET2 (TET2 Produkte)
    Synonyme
    KIAA1546 antikoerper, MDS antikoerper, Ayu17-449 antikoerper, E130014J05Rik antikoerper, mKIAA1546 antikoerper, RGD1311625 antikoerper, tet methylcytosine dioxygenase 2 antikoerper, TET2 antikoerper, Tet2 antikoerper
    Hintergrund
    TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14 % of patients with JAK2V617F-positive myeloproliferative neoplasms, and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia. Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.Synonyms: KIAA1546, Methylcytosine dioxygenase TET2
    Gen-ID
    54790
    NCBI Accession
    NP_001120680
    Pathways
    Warburg Effekt
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