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CDKN2B Antikörper

CDKN2B Reaktivität: Human WB, IF, IP Wirt: Maus Monoclonal 1F6 unconjugated
Produktnummer ABIN1449282
  • Target Alle CDKN2B Antikörper anzeigen
    CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
    Reaktivität
    • 71
    • 30
    • 29
    • 15
    • 15
    • 13
    • 5
    • 2
    • 2
    • 1
    Human
    Wirt
    • 64
    • 7
    • 1
    Maus
    Klonalität
    • 66
    • 6
    Monoklonal
    Konjugat
    • 32
    • 7
    • 6
    • 6
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CDKN2B Antikörper ist unkonjugiert
    Applikation
    • 49
    • 35
    • 29
    • 28
    • 18
    • 14
    • 11
    • 9
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)
    Spezifität
    This antibody reacts with p15INK4b (15 kDa).
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human (HeLa, 293T, transfectant), does not react with Mouse (NIH/3T3, P3U1) and Rat (PC12, Rat1)
    Aufreinigung
    Protein A agarose
    Immunogen
    GST-full length human p15INK4b
    Klon
    1F6
    Isotyp
    IgG1
    Top Product
    Discover our top product CDKN2B Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 50 % glycerol, pH 7.2. Contains no preservatives.
    Konservierungsmittel
    Without preservative
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Upon receipt, store (in aliqouts) at -20 °C.
  • Target
    CDKN2B (Cyclin-Dependent Kinase Inhibitor 2B (p15, Inhibits CDK4) (CDKN2B))
    Andere Bezeichnung
    CDKN2B / p15INK4b (CDKN2B Produkte)
    Hintergrund
    Progression through the G1 phase of the cell cycle is regulated in part by the D-type cyclin-dependent kinases, cdk4 and cdk6. p15INK4b is a specific inhibitor of cdk4/cdk6 and is periodically expressed during cell cycle. Induction of p15INK4b is important for TGFß-mediated cytostasis in epithelial cells but not in hematopoietic cells, it may act as an effector of TGF-ß mediated cell arrest.Synonyms: Cyclin-dependent kinase 4 inhibitor B, MTS2, Multiple tumor suppressor 2, p14-INK4b, p14INK4b, p15-INK4b
    Gen-ID
    1030
    NCBI Accession
    NP_004927
    UniProt
    P42772
    Pathways
    Zellzyklus, Mitotic G1-G1/S Phases
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